Purpose. This study aims to evaluate the process of brain development in neonates using combined amide proton transfer (APT)\nimaging and conventional magnetization transfer (MT) imaging. Materials and Methods. Case data were reviewed for all patients\nhospitalized in our institution�s neonatal ward. Patients underwent APT and MT imaging (a single protocol) immediately following\nthe routine MR examination. Single-slice APT/MT axial imaging was performed at the level of the basal ganglia. APT and MT ratio\n(MTR) measurements were performed in multiple brain regions of interest (ROIs). Data was statistically analyzed in order to assess\nfor significant differences between the different regions of the brain or correlation with patient gestational age. Results. A total of\n38 neonates were included in the study, with ages ranging from 27 to 41 weeks� corrected gestational age. There were statistically\nsignificant differences in both APT and MTR measurements between the frontal lobes, basal ganglia, and occipital lobes (APT:\nfrontal lobe versus occipital lobe
Loading....